Symbol
Name
ID

Rnaseh2a
ribonuclease H2, large subunit
MGI:1916974

Phenotype annotations related to immune system

Darker colors indicate more annotations

Human Phenotypes

Increased circulating antibody level

Lymphocytosis

Chronic lymphatic leukemia

Generalized lymphadenopathy

Splenomegaly

Hepatosplenomegaly

Hepatitis

Increased circulating interferon-gamma concentration

Increased circulating Interferon-alpha concentration

Chilblains

Atopic dermatitis

Skin rash

Myositis

Panniculitis

Pneumonia

Autoimmunity

Antiphospholipid antibody positivity

Recurrent lower respiratory tract infections

Disease(s) Associated with RNASEH2A

Aicardi-Goutieres syndrome

Mouse Phenotypes		increased spleen weight	increased monocyte cell number	abnormal innate immunity	decreased susceptibility to Riboviria infection
Availability	Mouse Genotype	increased spleen weight	increased monocyte cell number	abnormal innate immunity	decreased susceptibility to Riboviria infection
	Rnaseh2a^tm1Crh/Rnaseh2a^tm1Crh
	Rnaseh2a^em1(IMPC)Tcp/Rnaseh2a⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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